BioPsy Webzine Vol 3, Number 5, November 1998
- sign up for a free BioPsy Webzine Subscription
Back to the Biopsy Back Issue Archive
TABLE OF CONTENTS
- editors brief note
- front of webzine matters
-
1)Futurehealths February 99 Winter Brain Meeting has
become a center for a plethora of Events:
- 1a)-the main Winter Brain Meeting: update on speakers and panel discussions
- 1b)-Pre-conference 2nd Annual Optimal Functioning Course
- 1c)-Pre-conference Neurofeedback Foundations Course
- 1d)-pre-conference Joel & Judith Lubar Comprehensive Neurofeeedback course
- 1e)-pre-conference Barry Sterman Topometric Brain Mapping for NF Course
- 1f) post conference Courses
- -EEG Spectrum
- -Len Ochs Flexyx course
- -Zengar Institute post-conference Biograph Training course
- 2) A)Equipment Specials and recent used and demo systems/equipment available
- 2) B) New website updates
- 2) C) Cool website sightings
- 2) D) New books available from Futurehealth
- The Human Frontal Lobes Functions and Disorders Edited by Bruce L. Miller and
Jeffrey L. Cummings
-
- Biofeedback new paperback edition 908 Pages, $40 Hardcover: $75.00
A Practitioner's Guide: Second Edition Mark S. Schwartz Foreword by Frank Andrasik
- 3) 26 Quotations on Relaxation by: The Beatles,
Franklin, Pascal, Emerson, Tennyson, Seneca. Stanislavski, Mencius, James, Hubbard,
Epictetus, Cervantes, DaVinci, Dryden, and more.
-
- 4)"Normal" Brains Show Abnormal PET Scans
- What is a "normal" brain? The results of a research study published in
this month's Annals of Neurology demonstrate that some of the apparently normal relatives
of patients with neurological disease in fact have abnormal brain patterns.
5) OFFICE DESIGN; Environment of psychotherapists' offices may affect client attitudes
6) Orgasms and Epilepsy website address http://www.duke.edu/~aga2/Daniel.html
-
- 7) Depression, High Stress Costliest Worker Health
Risks
- 8)AHCPR ANNOUNCES NEW EVIDENCE REPORT TOPICS
The Agency for Health Care Policy and Research (AHCPR) today announced the next topics
to be investigated by the Agency's Evidence-based Practice Centers (EPCs). The EPCs will
conduct rigorous, comprehensive reviews of the relevant scientific literature on these
topics, including meta-analyses and cost analyses, if appropriate. Their findings will be
published as evidence reports or technology assessments.
9) Meditation Program Helps Relieve Chronic Pain
- To help treat chronic pain patients, a psychologist has developed an effective
pain/stress management program which combines both meditation and yoga exercises with
medical and psychological treatment. 85 percent of participants who used meditation
practices to self-regulate pain reported a relief from symtpoms.
-
- 10) HUMAN BRAIN TRANSPLANTATION PROTOCOL APPROVED TO REVERSE NERVE AND
BRAIN DAMAGE
Description: Scientists at Cedars-Sinai Medical Center are ready to start a human
treatment protocol that can reverse nerve and brain damage caused by stroke, Parkinson's
disease, epilepsy and spinal cord injuries. The treatment involves removal and
regeneration of carefully targeted brain cells, which are then re-introduced into the
patient, where growth continues and the brain is repaired.
-
- 11) Scientists Report Brain's Central Switching System Can Be
Remodeled
- The thalamus, the brain's central switching center for relaying sensory
information to the brain's somatosensory cortex, "remodels" after sensory nerves
are severed, scientists from Wake Forest University School of Medicine and the University
of California at Davis report in today's issue of Science.
-
- 12) Taking Self Regulation, Biofeedback and Self Responsibility to the Next
Level. Rob Kall
-
- 13) Adult Brains Make New Connections After Injury The adult brain appears
to have a surprisingly strong built-in capacity for change, a study suggests, creating the
possibility for innovative treatments for brain disorders.
- Editorss Column
- Its been the summer since the last webzine was sent out. This issue is loaded with
articles I hope youll enjoy. We just got some great news that our hard work at
producing a quality product has paid off. Our website -- Neurofeedback Central
(http://www.futurehealth.org/neurofeedback central.htm) is rated #1 of the "Top 10
Results from Direct Hit " a search program which finds the top ten most visited sites
for whatever topic you enter in the search engine.
-
- Of course, the latest news about the 99 Winter Brain/Mind Meeting is included. The
last minute news about speakers, panels and workshops is quite exciting. The NIH concencus
hearings on ADHD proved interesting, It seems they found that most of the field of ADHD--
diagnosis, treatment of older children, adults, lnog term use of medications -- are all
inadequately researched. So, alternative approaches like biofeedback, nutritional
approaches, etc. may have a more even playing field. .
- Personally, Ive opened up a new office-- The Center For Optimal Functioning-- with
my partner, Rhonda Greenberg, Psy.D., which will provide a range of biofeedback,
neurofeedback, coaching and psychotherapy services in Newtown, PA 215-504-1700 http://www.futurehealth.org/CFOL.htm
-
-
- front of webzine:
- Feel free to forward this intact, entire webzine to anyone
you feel might be interested in seeing it.
- Posting to websites or BBSs is also permitted as long as
the entire contents is posted.
-
- Published and Edited by Rob Kall, FUTUREHEALTH Inc,
biofeedback, neurofeedback
- and Stress Management tool supplier founder and organizer
of the 7th annual Winter
- Conference on Brain/Mind Function/EEG, Modification &
Training: Neurofeedback,
- qEEG, ADD, Sound/Light, Consciousness, Peak Performance
Advanced Meeting
- Colloquium (formerly Known as the Key West EEG Meeting)
- Rob Kall, M.Ed.
- FUTUREHEALTH inc
211 N. Sycamore, Newtown, PA 18940, 215-504-1700 fax 215-860-5374
- BioPsy@futurehealth.org
- Editorial material wanted: if you've written something of
interest to fellow travelers, we'd like to
- have an opportunity to evaluate it for our publication,
including reprints of already published
- material.. Announcements about meetings and workshops will
also be considered for inclusion.
- Past issues of BioPsy are available at FUTUREHEALTH's and
Rob
- Kall's Website on the BioPsy Back Issues Archive:
- http://www.futurehealth.org/biopsycy.htm
-
- -----------------------------------------------------------------------------------------------------
-
- At Futurehealth, We buy, sell and trade New ,
Demo & Used BioNeuroFeedback Equipment Systems,
- great prices, service, package deals. Call us!
- Bio-Stress Squares, books, tapes, Disposables
-
Specials and new items:
- -New: Free 4 hour Biograph training Video with
all Procomp Sales ($189 if purchased separately
- Procomp with BIograph 15% off the rertail price
for pre-paid cash/check!
- -Plus, we now have animated cartoon and puzzle
game add-ons for Procomp $250 .
-EMG stand-alone trainer red LED light-bar
display, with high and low threshold, pleasant audio: $275 for the next 4 customers
- -Respiratory Sinus Arrhythmia Trainer Special reduced from $500 to $395. Add $400
(Usually $500 for software and interface)
The prices of the audio and video foundations Neurofeedback course have gone up. Buy it
at the old price until Dec 10th.
- HiTech Stress Cards, $110/100 $795 for first time orders
of 1000
-
- Brain Master Windows compatible, full function
dual-channel trainers are now available at a great new price of $950 each. These give you
the ability to display two channels in a brain mirror display as wellas have full access
to all frequencies.
Mindset brain mapper $2399 (just add headgear.)
Used Focus 1000 $1995 (includes portable color computer)
Demo Procomp Unit with four sensors $1995 (older, non-eeg, non-biograph compatible
unit, good for stress management training.) This will run great on a 486 notebook. We'll
include the color notebook for a total $2450 price.
Standalone EEG unit $495
The best thermal biofeedback package deal around: Audio Thermal Trainer combined with
digital numeric readout unit $79.00
-
- 1)Futurehealths February 99 Winter Brain Meeting has become a center for a
plethora of Events:
- 1a)-the main Winter Brain Meeting: update on speakers and panel discussions
- Winter Brain Conference Featured speakers to include:
- Bob Thatcher QEEG
- Bernie Brucker, neuro-rehab
- Patricia Carrington power therapies (EMDR, TFT, EFT,) clinically standardized meditation
- Hyla Cass, M.D. author of books on St. Johns Wort & Kava
- Gary Craig: EFT: A Paradigm Shift: "We are on the Ground Floor of A Healing
Highrise"
- Joseph Horvat- EEG phase & synchrony
- Martha Lappin working with Magnetoencephalograph Stimulation
- Joel &Michelle Levy Explaining theSpectrum of Self-Regulation:
- Mastery, Mystery, & the Technologies of Transformation
- S.Louise Norris Peak Perfmance
- Frank Echenhoffer, Ph.D. EEG & Consciousness researcher, BF pioneer
- Karl Pribram brain researcher
- Steve Wall Deep EEG Training & the Evolution of Human Consciousness
- Tom Allen neurobehavioral continuum topics
- Anand Akerkar FDA issues
- Valdeane Brown, Ph.D. main trainer for TT Biograph,
- Tom Budzynski, enhancing mental functioning in the aging
- Tom Collura brainmaster developer, and listerver major domo
- Frank & Mary Deits spa BF
- Jay Gunkelman QEEG mapping, interpretation,
- Cory Hammond: Managing Abreactions, Reframing, and Memory Integration During Alpha/Theta
Training: Techniques and
- Liability Protection in a False Memory Era.
- -Thom Hartmann Best selling author of 6+ books on ADD
- -Michael Hutchison author Megabrain, Megabrain Zones
- Julian Isaacs alpha/theta groups
- Rob Kall Co-editor Biofeedback Theory & Practice, Co-author CAM Scan, Biopro
Software
- Joel F. Lubar, Ph.D. NeurofeedbackBF pioneer
- Judith Lubar integrating family & psychotherapy
- Sig and Sue Othmer EEG Spectrum leader founders
- Lynda Thompson ADD/HD
- Linda Vergara NF in school
- Susan Norris Student Performance Enhancement, Practice Economics, Depression pre-post
QEEG
- Paul Lehrer Respiratory Sinus Arhythmia, Chaos, Zen Meditator Psychophysiology...
- David Joffe, Steve Larsen Linda Mason Len Ochs Peter Rosenfeld Carole Schneider
Gary Schwartz Barry Sterman Michael Thompson Hershel Toomim, George Von Hilsheimer
- and at least 20 more great speakers and 30+ workshops yet to be listed.
-
-
- Panel Discussions are one of the most stimulating parts of our meetings. 1999 Panel
topics:
- -Synchrony/coherence
- -Nonlinear Dynamical Systems/Chaos
- -QEEG, Brain imaging and Brain Changing
- -Nutrition, Smart Drugs, Nutrients & Superhormones
- -Brain/Mind Stimulation (light, sound, electrical, magnetic, etc.)
- -The Neurobiology of the Power Therapies
-
- Pre-conference events:
- 1b)- 2nd Annual Optimal Functioning Course
http://www.futurehealth.org/99optima.htm
-
- Were still accepting proposals for presentations and workshops.
- 1c)- Neurofeedback Foundations Course Feb 4, 9-9 with Joel Lubar, Siegfried Othmer, Paul
Swingle, Valdeane Brown, Rob Kall
-
- 1d)- Joel & Judith Lubar Comprehensive Neurofeeedback
course
- http://www.futurehealth.org/lubarcou.htm for registration details.
Joel
& Judith Lubar
|
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2 day Comprehensive Neurofeedback
Course
in Evaluation, Applications & Protocols in
ADD/HD, Depression, Anxiety, closed head injury
other co-morbid disorders and Optimal Functioning.
Before the Winter Brain Conference Feb 3,4 1999,
Palm Springs, CA
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Workshop Outline:
1) Research and physiological underpinnings for the field of neurofeedback;
- 2) Reading and interpreting the EEG, including the following:
a) Meaning of EEG terminology (Hz., amplitude, bandpass,
frequencies, Greek letter designations - and meanings for theta, alpha, beta, lambda, and
gamma);
b) Recognition of the different EEG patterns (signatures) both on
line and off line;
c) Interpretations of patterns and their relevance to the particular
syndromes including ADD/ADHD, seizures, depression, alcohol and drug dependency, LD,
Tourette's Syndrome, mild head injury;
d) Typical EEG patterns for different syndromes in normal awake
patients;
e) Typical EEG patterns for ADD/ADHD and other syndromes, age related
differences;
f) Atypical EEG patterns which indicate a need for further EEG
studies and/or neurological evaluation;
g) Basic electrical concepts necessary to good recording of data
(impedance, frequency response, common mode rejection, sensitivity or gain, amplifier
noise, offset potentials, detection of electrode artifacts;
h) Reading a Fast Four ier Transform and Power spectral analysis;
i) Elementary trouble shooting;
j) Evaluation for different syndromes;
k) Atypical patterns and subpatterns for different syndromes;
l) Using the FFT or Fast Fourier Transform for the clinical
evaluation;
m) Read ing Topographical Brain Maps;
n) Subtypes of ADD classifications based on maps;
o) Patterns for other psychiatric diagnoses.
3) Clinical Sessions will cover:
a) Changing parameter settings to improve learning in the middle
of successful treatment;
b) Deciding if the parameter changes are needed in a treatment when
learning does not seem to occur;
c) Setting up the session segments;
d) Deciding on which activities besides straight feedback segments
are needed during the session (and ordering these within the session);
e) Determining the length of each session segment initially and
changing the length of the segment across sessions;
f) When and how to change burst length for training;
g) Graphing the data and determining the course of treatment;
h) Using graphs as guides for parameter changes;
i) Electrode placement;
j) Measuring for correct place ment;
k) Skin preparation;
l) Impedance and voltage offset measuring;
m) Interaction of Neurofeedback with pharmacotherapy.
4) Clinical Evaluation Process:
a) ADD/ADHD, Depression, LD, Bipolar disorder, alcohol or drug
withdrawal, or combination of the above;
b) Learning to separate similar attentional behavior problems in all
of these different syndromes;
c) History taking;
d) Questions to the client about "disappearing" from the
task at hand;
e) Questions about possible associated LD's;
f) auditory, visual receptive and expressive problems;
g) verbal expressive problems;
h) Questions about mem ory (short and long term) and how it matches
the strength or weakness of the patient's style;
i) Does this match or mismatch with parental styles;
j) presence of conduct disorder and parental limit setting;
k) Genogram to determine family history includin g ADD, Depression,
Tourette's Syndrome, Alcohol, Drug and Abuse problems;
l) School Interventions and integration with treatment;
m) How to deal with difficult cases, including indications of success
and failure and need for Co-Therapy for parents.
- 5. Quantitative EEG (QEEG) analysis, including
coherence, phase, asymmetry , and frequency compared with normative databases for the
evaluation of ADD/HD and mild closed head injury.
-
- Registration Info:
-
- $450 pre-reg before Dec 15
- $475 before Jan 15
- $499 on site.
-
You must use a registration form to register.
1e)- Barry Sterman Topometric Brain Mapping for NF Course
Feb 2-4
http://www.futurehealth.org/sterman.htm for registration details.
COURSE OBJECTIVES
This course provides an in-depth review of the essential building blocks for
understanding and proper application of quantitative electroencephalography in the areas
of client evaluation and neurofeedback training. These components include a) the
physiological basis of the EEG, b) the functional relevance of frequency/topography
patterns and c) the evaluation of client status and change with training. For the latter
it introduces and describes a new software program called the SKIL Topometric.
Dr. Sterman, a professor in the Departments of Neurobiology and Psychiatry at UCLA, is
uniquely qualified to present this course. His basic studies of the EEG in animals have
contributed significantly to current neurophysiological models, his past and ongoing
studies of EEG functional dynamics in humans were germinal to the field of neurofeedback
and are currently challenging some time-honored concepts in EEG, and his pioneering
quantitative studies of the EEG as a tool for the evaluation of pathology and training
outcomes in epileptics set the standards for the field of neurofeedback.
Grants and contracts from the US federal government supported all of this research.
Further, as Dr. Sterman likes to say, all of the facts and concepts presented in this
course are based on published articles in respected journals and on findings replicated at
more than one facility. When he reaches into his extensive research and clinical
experience to express an opinion, he makes it very clear that the jury is not yet in on
that issue.
COURSE OUTLINE
I. A Brief History of the EEG and Neurofeedback
II. Physiological Origins of the EEG
A. Where Does the EEG Signal Come From?
1. Ionic current flow in neurons
2. EPSPs and IPSPs
B. Field Potential Changes at the Cortical Surface
1. Cortical pyramidal cells: structure, orientation, input
2. Cell orientation, dipoles and surface field potentials
C. Thalamic Oscillatory Mechanisms
1. Organization of thalamic relay systems
2. Relay cell behavior
3. Inhibitory burst discharge
4. The Nucleus Reticularis Thalami
5. Projections to cortex and cortical circuits
D. The "athalamic cat", isolated cortex, and slow EEG activity
E. Normal frequency modulation
1. Relationship of thalamic cell membrane voltage to frequency patterns
2. The Graded Polarization model
3. The Independent Generator model
F. Abnormal frequency modulation
1. Cortical hyperexcitability
2. GABA receptor types and characteristics
3. Video presentation
G. Problems with Terminology
III. The Normal EEG
A. Before QEEG: Basics from higher mammals
1. SMR
2. PRS
3. State progression
B. The Human EEG
1. Changes over Time
a. Developmental considerations
b. Sleep and waking
c. Biological cycles diurnal modulation
2. Functional correlates of frequency components
a. The dimension and elements of attention
b. Movement and motor states
IV. Methods and Issues in Quantitative EEG Analysis
A. Recording methods
1. Common-mode rejection
2. The issue of reference
3. Monopolar vs. Bipolar
B. Signal acquisition
1. Montages
2. Digitizing
3. Artifact
4. Signal extraction
C. Signal analysis
1. FFT and band-pass
2. Sampling rate
3. Windowing
4. Band construction
5. Averaged epochs
V. Collecting the Data
A. Patient records and intake interview
B. Patient preparation
C. Data protocols
D. Observing the patient
E. Educating the patient
VI. Analysis of the Data
A. Visual Evaluation of the Raw Data
1. Artifact removal
2. Recognizing significant transients
3. Deriving initial functional correlates
B. Topographic Evaluation and Bands Selection
1. Topographic maps
2. Compressed spectral arrays
3. About normative databases
VII. The SKIL Topometric
1. The Normative Database
a. Displays and statistical evaluation
b. State and transition corrections
c. Reliability
d. State comparisons
e. Coherence and covariance
2. Topometric Analysis: Some Clinical Characteristics
a. Seizure disorders
b. Attention deficit and related disorders
c. Head injury
d. Tourett Syndrome
e. Anxiety and Depression
f. Others
3. How to use the SKIL Topometric
a. Pt. Reports: The interactive index for report construction
b. Use of the database.
c. Interpretation and application to neurofeedback
VIII. Future Developments
A. The Event-related EEG Response: applications to evaluation and training
Sterman Course Registration fee:
$550 on-site, $450 until Dec. 5th, $495 until Dec 30th, $525 until Jan 25th.
.Or, Register and buy a Mindset EEG at a combination discounted price (save $100 when
combining registration and purchase.)
__Add the SKIL Sterman Topometric Database for $2000
1f)-post conference Courses
Gary Craig Advanced Course on EFT Emotional Freedom
-EEG Spectrum Alpha Theta Course
-Len Ochs Flexyx course
-Zengar Institute post-conference Biograph Training course
2) A)Equipment Specials and recent used and demo systems/equipment available
2) B) New website updates Futurehealths website continues to get better and
better. Our new navigation bar makes it easier than ever to find what you are looking for
when it comes to biofeedback, neurofeedback, stress or pain management.
2c)
New books available from Futurehealth
The Human Frontal Lobes
order from Futurehealth for $75 plus $4.50 shipping
Functions and Disorders
Edited by Bruce L. Miller and Jeffrey L. Cummings
Pages: 550 Publication Date: October 1998
Recent years have seen exciting advances in our understanding of the human frontal lobes
and their role in diverse cognitive processes, social behaviors, and psychiatric
disorders. This volume brings together current research on these important regions of the
brain, examining their functions in both health and disease. Significant findings on
anatomy, chemistry, and physiology are first presented. Next, chapters address such
neuropsychological functions as working memory, attention, inhibition, idea and word
generation, and language, tracing their links to the frontal lobes and describing new and
established approaches to assessment and testing. Proceeding to clinical manifestations of
pathology, contributors examine the impact upon the frontal lobes of tumors, trauma, and
various neurological diseases, and explore the role of frontal lobe dysfunction in
psychiatric disorders including schizophrenia, obsessive-compulsive disorder, depression,
and antisocial behavior.
Preface
I. Neuroanatomy of the Frontal Lobes
1. Frontal-Subcortical Circuits, Tom and Cummings
2. Frontal Lobe Anatomy and Cortical Connectivity, Kaufer and Lewis
3. Structural and Functional Asymmetries of the Human Frontal Lobes, Geschwind and
Iacoboni
4. Gross Morphology and Architectonics of the Frontal Lobes, C. A. Miller
5. The Evolution and Phylogenetic History of the Frontal Lobes, Banyas
6. Neuroimaging and the Frontal Lobes: Insights from the Study of Neurodegenerative
Diseases, Jagust
II. Neurochemistry and Neurophysiology of the Frontal Lobes
7. Serotonin and the Frontal Lobes, Robert, Aubin-Brunet, and Darcourt
8. Acetylcholine and Frontal Cortex "Signal-to-Noise Ratio," Hasselmo and
Linster
9. Dopamine Projections and Frontal Systems Function, Swartz
10. Neurotransmitters and Neuromodulators in Frontal-Subcortical Circuits, Feifel
11. Cognitive Functions of the Frontal Lobes, Fuster
12. Neuroimaging and Activation of the Frontal Lobes, Grady
III. Neuropsychological Functions of the Frontal Lobes
13. Bedside Frontal Lobe Testing: The "Frontal Lobe Score," Ettlin and
Kischka
14. Neuropsychological Assessment of Executive Functions: Impact of Age, Education,
Gender, Intellectual Level, and Vascular Status on Executive Test Scores, Boone
15. Language and the Frontal Lobes, Kertesz
16. Frontal Lobe Dysfunction and Patient Decision Making about Treatment and Participation
in Research, Fitten
17. Memory and the Frontal Lobes, Yener and Zaffos
18. Neuropsychiatry of the Right Frontal Lobe, Edwards-Lee and Saul
19. Experimental Assessment of Adult Frontal Lobe Function, Grafman
IV. Diseases of the Frontal Lobes
A. Neurology
20. Clinical and Pathological Aspects of Frontotemporal Dementia, Brun and Gustafson
21. Vascular Diseases of the Frontal Lobes, Chui and Willis
22. Extrapyramidal Disorders and Frontal Lobe Function, Litvan
23. Lewy Body Disorders, McKeith
24. Frontal Lobe Tumors, Nakawatase
25. Psychosurgery, Weingarten
26. Infectious, Inflammatory, and Demyelinating Disorders of the Frontal Lobes, Scharre
27. Traumatic Brain Injury, Schnider and Gutbrod
B. Psychiatry
28. Schizophrenia and Frontal Lobe Functioning, W. Perry, Swerdlow, McDowell, and Braff
29. Obsessive-Compulsive Disorder and the Frontal Lobes, Rubin and Harris
30. Depression and Frontal Lobe Disorders, Starkstein and Robinson
31. Aggression, Criminality, and the Frontal Lobes, Pincus
32. Anterior Temporal Lobes: Social Brain, B. L. Miller, Hou, Goldberg, and Mena
33. Cholinergic Components of Frontal Lobe Function and Dysfunction, E. K. Perry
34. Frontal Lobe Development in Childhood, Samango-Sprouse
Biofeedback new paperback edition 908 Pages, $40 Hardcover: $75.00
A Practitioner's Guide: Second Edition Mark S. Schwartz Foreword by Frank Andrasik
"Unquestionably the definitive book on biofeedback today....For anyone entering the
biofeedback field, seeking a comprehensive reference or update on the field, or studying
for BCIA certification, this text should be consulted first....It is informative and
thought-provoking even for the most experienced biofeedback practitioner, yet it is
accessible to the intelligent beginner."
-Biofeedback and Self-Regulation
Publication Date: August 1998
3) Quotations on Relaxation 26 quotations
OBSESSION, INSOMNIA, ANXIETY, RELAXATION
You know I can't sleep, I can't stop my brain
You know it's three weeks, I'm going insane.
You know I'd give you everything I've got for a little peace
of mind.
Beatles, I'm so tired
CASTI, GIAMBATTISTA, 1721-1804
RELAXATION, MEDITATION, QUIET, THINKING
"Whoso doth everyday employ
In doing naught and thinking less,
Tis he alone can life enjoy
He only knows true happiness."
Casti,Giambattista, I Dormienti
WORRY. RELAXATION, SADNESS, DEPRESSION
"Sing away sorrow, cast away care."
Cervantes
ART, SELF KNOWLEDGE, RELAXATION, REST
" It will be useful also to quit his work often, and
take some relaxation, that his judgement may be clearer at his return; for too
great application and sitting still is sometimes the cause of many gross errors."
DaVinci, Leonardo, A TREATISE ON PAINTING
RELAXATION
For not to live at ease is not to live.
Dryden, Translation of Persius
CHARACTER, RELAXATION, SOLITUDE
"What is the product of virtue? Tranquility."
Epictetus
RELAXATION, THERMAL BIOFEEDBACK, BLOOD, HEART
"Head and feet keep warm, the rest will take no
harm."
Fuller, Thomas, Gnomologia 6255
The time to relax is when you don't have time for it.
Sydney J. Harris
RELAXATION, PEACE, SERENITY, CALM, PEACEFUL, ANGER,
EVEN, COPING, EMOTION, FEELING, ADVERSITY, STRESS, VOLITION, SELF CONTROL
"Remember to preserve an even mind in adverse
circumstances, and likewise in prosperity a mind free from overweening joy."
Horace, Odes
RELAXATION, PLAY, SILLY, FUN
The man who does not relax and hoot a few hoots
voluntarily, now and then, is in great danger of hooting hoots and standing on his head
for the edification of the pathologist and trained nurse, a little later on.
The madhouse yawns for the person who always does the proper
thing.
Elbert Hubbard
"You Americans wear too much expression on your faces.
You are living like an army with all its reserves engaged in action. The duller
countenances of the British population betoken a better scheme of life. They suggest
stores of nervous force to fall back upon, if any occasion should arise that requires it.
...you ought somehow to tone yourselves down. You really do carry too much expression, you
take too intensely the trivial moments of life."
Dr. Clouston (asylum physician) quoted by James. Many of us,
far from deploring it, admire it. ...Intensity, rapidity, vivacity of appearance, are
indeed with us something of a nationally accepted ideal... Bottled lightning, in truth, is
one of our American ideals, even of a young girl's character.
James, William, 1899, TALKS TO TEACHERS ON PSYCHOLOGY: And To
Students On Some of Life's Ideals, Chapter 1-The Gospel of Relaxation
"In one sense, the more or less of tension in our faces
and in our unused muscles is a small thing: not much mechanical work is done by these
contractions. But it is not always the material size of a thing that measures its
importance, often it is its place and function. One of the most philosophical remarks I
ever heard was by an unlettered workman who was doing some repairs at my house many years
ago. "There is very little difference between one man and another," he
said,"when you go to the bottom of it. But what little there is , is very
important." And the remark certainly applies to this case. The general
over-contraction may be small when estimated in foot pounds, but its importance is immense
on account of its effects on the over-contracted person's spiritual life. This
follows as a necessary consequence from the theory of our emotions to which I made
reference at the beginning of this article. For by the sensations that so incessantly pour
in from the over-tense excited body the over-tense and excited habit of mind is kept up;
and the sultry, threatening, exhausting, thunderous inner atmosphere never quite clears
away.
"If you never wholly give yourself up to the chair you
sit it, but always keep your leg and body muscles half contracted for a rise; if you
breathe eighteen or nineteen instead of sixteen times a minute, and never quite breath out
at that,-- what mental mood can you be in but one of inner panting and expectancy, and how
can the future and its worries possibly forsake your mind? On the other hand, how can they
gain admission to your mind if your brow be unruffled, your respiration calm and complete
and your muscles all relaxed?
James, William, 1899, TALKS TO TEACHERS ON PSYCHOLOGY: And To
Students On Some of Life's Ideals, Chapter 1-The Gospel of Relaxation
The intellect which never relaxes is very liable to
error.
Joseph Joubert
Relaxation frees the heart.
Courage opens the heart.
Compassion fills the heart
Kall
RELAX, RELEASE, PLAY, JOY, HAPPINESS, LETTING GO,
"The great man is he who does not lose his child's
heart."
Mencius (372-289 BC)
RELAXATION, CALM, PEACE, STILLNESS
Happiness is the harvest of a quiet eye.
O'Malley, Austin
RELAXATION
"An open brow indicates an open heart."
Schiller
EMOTION, FEELING, ADVERSITY, STRESS
RELAXATION, PEACE, SERENITY, CALM, PEACEFUL, ANGER,
EVEN,
"It is the nature of a great mind to be calm and
undisturbed."
Seneca, De Clementia
SOUTH, ROBERT
RELAXATION, TRANQUITIY, ALTERED-STATE
"When the supreme faculties move regularly, the inferior
passions and affections following, there arises a serenity and complacency upon the whole
soul, infinitely beyond the greatest bodily pleasures, the highest quintessence and elixir
of worldly delights."
At times of great stress it is especially necessary to
achieve a complete freeing of the muscles.
Stanislavski, Constantin An Actor Prepares, Ch. 4 Relaxation
of Muscles
RELAXATION, PEACE, SERENITY
"There is no joy but calm."
Tennyson, The Lotus Eaters, Choric Song
VAUVENARGUES, LUC, MARQUIS DE: 1715-1747
RELAXATION
Solitude is to the mind what Dieting is to the
body.
Vauvenargues, Luc Marquis De,
RELAX, CASUAL, CHILD
I do not think that any civilization can be called complete
until it has progressed from sophistication to unsophistication, and made a conscious
return to simplicity of thinking and living.
Lin Yutang, The Importance of Living
ART, RELAXATION
I think sculpture and painting have an effect to teach us
manners, and abolish hurry.
Emerson
RELAXATION, SELF CONTROL
"He that can compose himself, is wiser than he that
composes books."
Franklin, Benjamin, POOR RICHARD'S ALMANAC
ANXIETY, QUIET, MIINDFULNESS, RELAXATION, PEACE, CALM
All mankind's troubles are caused by one single thing, which
is their inability to sit quietly in a room.
Pascal, Pensees, II, 139
We must not divert the mind, except to relax it, but
at the proper time; to relax it when it is necessary, and not otherwise; for
whoever relaxes inappropriately wearies; and whoever wearies inappropriately relaxes,
for people then withdraw attention altogether: so pleased is the malice of desire to
do just the opposite of what one wishes to obtain from us without giving us pleasure,
which is the change for which we give all that is desired.
Pascal, Pensees
----------------------------------------------
4) "Normal" Brains Show Abnormal PET Scans
Library: MED
Keywords: DYSTONIA NY DYT-1 ITD IDIOPATHIC TORSION DYSTONIA
Description: What is a "normal" brain? The results of a research study
published in this month's Annals of Neurology demonstrate that some of the apparently
normal relatives of patients with neurological disease in fact have abnormal brain
patterns.
Media contact: Beckie Smith, American Neurological Association,
(612) 545-6284 theresagutoski@compuserve.com
"NORMAL" BRAINS SHOW ABNORMAL PET SCAN PATTERNS
Scientists are asking the question, What is a "normal" brain? The results of a
research study published in this month's Annals of Neurology demonstrate that some of the
apparently normal relatives of patients with neurological disease in fact have abnormal
brain patterns.
The researchers studied brain images of patients with an inherited form of the movement
disorder dystonia, as well as images of their relatives who have the same genetic defect
but do not have the disease. All the study subjects who had the genetic defect, even those
who tested "normal" on neurological tests, exhibited the same abnormal pattern
of brain activity.
Dystonia is movement disorder characterized by prolonged muscle contractions that can be
as mild as writer's cramp or as severe as contortions that affect the whole body and
confine the sufferer to a wheelchair. Some dystonias are caused by injuries to brain areas
that control movement, and others have a genetic cause, often appearing in childhood and
getting progressively worse.
One subset of dystonia patients has a clearly defined defect in a gene called DYT-1.
Although it is not known why this gene defect leads to dystonia, scientists have learned
that many people appear normal on routine neurological tests even though they carry gene
defect.
Using positron emission tomography (PET), researchers at North Shore University Hospital
in Manhasset, New York, and at Columbia Presbyterian Medical Center in New York City, took
a closer look at the brains of DYT-1 dystonia patients and their "normal"
relatives who carried the defective gene. They discovered that, compared to control
subjects who did not have the gene defect, both of these groups had abnormal patterns of
brain activity confined to the same brain networks.
"Thats a fascinating thing because it opens the big issue as to whether there
are a lot of people walking around in society that we view as 'normal' who may actually
have gene-specific abnormalities of brain function," said David Eidelberg, M.D.,
director of the Functional Brain Imaging Laboratory at North Shore University Hospital,
and lead author of the report.
In fact, says Eidelberg, more sophisticated neurological tests may turn up abnormalities
in the motor behavior of these "normal" people. Preliminary evidence from a
follow-up study suggests that they show subtle abnormalities when tested on complex
movement tasks.
In addition to the network of brain regions common to all the DYT-1 carriers, the
researchers identified a second network found only in the dystonia patients and only when
they were experiencing muscular contractions.
"The big question is why do some have the second network," said Eidelberg.
"There may be other genes involved, or there may be environmental causes."
The researchers will now try to refine their understanding of these brain networks, and
perhaps approach the question of how these two networks relate to the symptoms of
dystonia.
Eidelberg also predicts that the study will prompt researchers studying other inherited
diseases to look more closely at individuals who carry defective genes but do not appear
to manifest any disease. In a more general sense, he and his colleagues hope that by
identifying distinctive brain networks in neurologically normal persons, they can add to
the understanding of how genes affect human behavior.
Other authors of the study were James R. Moeller, Ph.D., of the Columbia College of
Physicians and Surgeons; Angelo Antonini, M.D., Ph.D., Ken Kazumata, M.D., Toshitaka
Nakamura, M.D., Vijay Dhawan, Ph.D., and Phoebe Spetsieris, Ph.D., of the North Shore
University Hospital and the New York University School of Medicine; Deborah DeLeon, M.S.,
and Susan B. Bressman, M.D., of Beth Israel Medical Center; and Stanley Fahn, M.D., of the
Neurological Institute in New York.
###
5) Psychotherapists' Offices May Affect Attitudes
Description: Dead plants, bad lighting and sagging couches are probably the last
things clients should encounter in their therapists' offices, according to a University of
Illinois architecture professor.
U of Ideas of General Interest -- October 1998 University of Illinois at Urbana-Champaign
Contact: Melissa Mitchell, Arts Editor (217) 333-5491; melissa@uiuc.edu
OFFICE DESIGN
Environment of psychotherapists' offices may affect client attitudes
CHAMPAIGN, Ill. -- Dead plants, bad lighting and sagging couches are probably the last
things clients should encounter in their therapists' offices, according to University of
Illinois architecture professor Kathryn Anthony.
"The physical environment of therapists' offices may well significantly influence the
attitudes and behavior of clients, but at this point we really don't know how,"
Anthony told members of the American Psychological Association at the group's annual
conference in San Francisco last August. In her presentation, titled "Designing
Psychotherapists' Offices: Reflections of an Environment-Behavior Researcher,"
Anthony challenged researchers, architects and therapists to collaborate to further
investigate relationships between office design and successful therapist-client
interactions.
The U. of I. researcher said she became interested in the topic after searching several
national research databases and finding "hardly anything at all." Although she
located 23 citations for office design and 3,358 for psychotherapy in Wilson Social
Sciences Abstracts, "none linked the two concepts." And of two citations in
Periodical Abstracts, only one -- a reference to a gas-filled mattress designed as a
therapeutic aid and personal relaxation/entertainment system -- even came close.
In the absence of hard data, Anthony undertook an informal survey of Division 12 APA
members, posting a query on its electronic bulletin board. She also sought anecdotal
information from therapist-acquaintances. She then combined the responses with her own
reflections as an architectural researcher to identify design factors that could play a
role in enhancing the experience of therapists and their clients. Among the factors and
corresponding relationships that emerged:
* Location. "If the office is right off a busy freeway intersection, the stress of
traffic can predispose one to an even more stressful session with the
psychotherapist."
* Placement and number of entrances and exits. "One therapist said that in seeking
out new office space she was concerned that the client could leave her office without
traveling through the waiting room, thus minimizing the need to interact or be seen in a
state of emotional fragility."
* Seating arrangements and seating comfort. "Is the therapist face-to-face with
clients, or side-by-side? Which is the most/least intimidating?" Regarding comfort,
"If it's too comfortable, do you feel like you are sinking into oblivion? Or do some
types of furniture actually help clients feel better?"
* Lighting. "Bright lights may seem cheerful to some clients, but glaring or
overwhelming to others."
* Windows. "Being able to see out widens your view of the world, and could have a
healing effect. By contrast, being in an enclosed environment could make you feel as if
the whole world is caving in on you."
-mm-
------------------------------------------------------------------
6) Orgasms and Epilepsy
Dostoyevski wrote:
- All you, healthy people, do not even suspect what happiness is, that happiness which we
epileptics experience during the second before the attack. During a few moments I feel
such a happiness that it is impossible to realize at other times, and other people cannot
imagine it. I feel a complete harmony within myself and in the world, and this feeling is
so strong and so sweet that for a few seconds of this enjoyment one would readily exchange
ten years of one's life-perhaps even one's whole life. (cited at the website described
below.)
At http://www.duke.edu/~aga2/Daniel.html you can read the rest of this article: if one
were to attempt to find the neural substrates for orgasms in the brain, the best bet would
be to search for patients who showed deficiencies in the brain in relation to orgasms. A
rare form of epilepsy called ecstatic epilepsy seems to fit this description well. During
or just prior to their attacks, patients characteristically describe having pleasurable
feelings that often culminate in orgasm. It is defined as a "temporal lobe seizure
phenomenon of intense pleasure, joy, and contentment" (Morgan 413). However, there is
another form of epilepsy mentioned in the medical literature that originates in the
parietal lobe of the brain and shows similar symptoms (Calleja et al., Ruff, Bachman), so
a neurobiological explanation of orgasms would have to take the activity of both cortical
regions into account.
===================================
American College of Occupational & Environmental Medicine
16-Oct-98
Depression, High Stress Costliest Worker Health Risks
Keywords: STRESS DEPRESSION HEALTH COSTS HEALTH RISKS
Description: Economic study of more than 46,000 employees finds stress and
depression have the greatest impact on worker health care costs. These risk factors
increased health care costs more than obesity, smoking or high blood pressure.
10/16/98
Contact: Kay Coyne kcoyne@acoem.org
Depression, High Stress Costliest Health Risk Factors Among Workers
Depression and high stress have the greatest impact on worker health care costs, concludes
an economic study of health risk factors, reported in the October issue of the Journal of
Occupational and Environmental Medicine, official publication of the American College of
Occupational and Environmental Medicine (ACOEM).
More than 46,000 employees from six nationwide organizations were followed for up to three
years, resulting in a database of over 100,000 person years, to evaluate ten modifiable
health risks and their associated impact on health care costs. The unusually large
database of information was compiled in cooperation with sustaining members of the
not-for-profit Health Enhancement Research Organization (HERO), Birmingham, Ala.
Industry officials note that there are several reasons why depressed and stressed workers
might have higher health care costs. Depression and stress may cause patients to seek care
for vague physical complaints; psychological or social problems may lead to more serious
health conditions; or depression or stress may be related to serious illness.
According to research led by Ron Z. Goetzel, Ph.D., of the MEDSTAT Group, Washington,
D.C., depression and stress seem to increase health costs more than obesity, smoking, or
high blood pressure. Health costs for workers reporting depression were 70 percent higher
than for nondepressed workers, the researchers found. Costs were elevated 46 percent for
workers who felt they were under a lot of stress.
Other health risks associated with significantly higher health care expenditures include:
high blood glucose, past tobacco use, current tobacco use, high blood pressure, and lack
of regular exercise.
High cholesterol, excessive alcohol consumption, and poor nutrition, had no apparent
effect on health costs, even though they are known to increase the risk of illness and
death. The results of the study were helpful in identifying patients likely to have
extremely high health care costs. For example, patients with risk factors for heart
disease had average medical costs of $3,800 per year, compared with about $1,200 for
patients lacking these risk factors.
New research will form the foundation for future cost effective and cost beneficial
prevention and health promotion efforts in the workplace, the study concludes.
ACOEM, an international society of 7,000 occupational physicians, provides leadership to
promote optimal health and safety of workers, workplaces, and environments.
Goetzel, Ron Z, et al. The Relationship Between Modifiable Health Risks and Health Care
Expenditures: An Analysis of the Multi-Employer HERO Health Risk and Cost Database Vol. 40
10 (October) pp. 843-854
8)AHCPR ANNOUNCES NEW EVIDENCE REPORT TOPICS
The Agency for Health Care Policy and Research (AHCPR) today announced the next topics
to be investigated by the Agency's Evidence-based Practice Centers (EPCs). The EPCs will
conduct rigorous, comprehensive reviews of the relevant scientific literature on these
topics, including meta-analyses and cost analyses, if appropriate. Their findings will be
published as evidence reports or technology assessments.
"These reports and assessments will provide evidence-based information on medical
conditions that can help reduce the uncertainty leading to inappropriate variations in
care," said AHCPR Administrator John M. Eisenberg, M.D. "AHCPR is committed to
ensuring that clinicians and patients, as well as health system leaders and policy makers,
have access to the best scientific evidence available to help them make informed health
care decisions."
Once distributed, the reports will facilitate translating evidence-based research findings
into clinical practice. The reports will form the basis of other organizations' efforts to
develop and implement their own practice guidelines, performance measures, review
criteria, and other clinical quality improvement tools. "Potential users of the
evidence reports and technology assessments include a wide range of health care providers,
medical and professional associations, health system managers, researchers, and others who
play key roles in the effort to improve the quality of health care services
nationwide," said Douglas Kamerow, M.D., M.P.H., who oversees AHCPR's Evidence-based
Practice Program. In addition, the reports may give health plans and payers information
needed to make informed decisions about coverage policies for new and changing medical
devices and procedures. (Reports from the 1997 topics assigned to the EPCs will be
available late in 1998.)
The new EPC topics are as follows:
1. Use of Erythropoietin in Hematology and Oncology
Blue Cross and Blue Shield Association Technology Evaluation Center, Chicago, Ill.
2. Management of Acute Chronic Obstructive Pulmonary Disease
Duke University, Durham, N.C.
3. Criteria for Determining Disability in Patients with ESRD
ECRI, Plymouth Meeting, Pa.
4. Treatment of Acne
Johns Hopkins University, Baltimore, Md.
5. Anesthesia Management During Cataract Surgery
Johns Hopkins University, Baltimore, Md.
6. Criteria for Weaning from Mechanical Ventilation
McMaster University, Hamilton, Ontario, Canada
7. Management of Cancer Pain
New England Medical Center, Boston, Mass.
8. Management of Acute Otitis Media
Southern California EPC/RAND Corporation, Santa Monica, Calif.
9. Prevention of Venous Thromboembolism After Injury
Southern California EPC/RAND Corporation, Santa Monica, Calif.
10. Management of Pre-term Labor
Research Triangle Institute and University of North Carolina at Chapel Hill, N.C.
11. Management of Chronic Hypertension During Pregnancy
University of Texas Health Sciences Center, San Antonio, Texas
12. Management of Unstable Angina
University of California, San Francisco, Calif., and Stanford University, Palo Alto,
Calif.
Contact: AHCPR Public Affairs, 301/594-1364
Howard Holland ext. 1374 (hholland@ahcpr.gov)
Salina Prasad ext. 1369 (sprasad@ahcpr.gov)
9) Meditation Program Helps Relieve Chronic Pain
To help treat chronic pain patients, a psychologist has developed an effective
pain/stress management program which combines both meditation and yoga exercises with
medical and psychological treatment. 85 percent of participants who used meditation
practices to self-regulate pain reported a relief from symtpoms.
CONTACT: Liz Inskip-Paulk - (806) 743-2143, adm1lap@ttuhsc.edu
Meditation Found to Help Chronic Pain Sufferers
(Lubbock) - In order to help treat chronic pain patients, a Texas Tech Medical Center
psychologist has developed an effective pain/stress management program which combines both
meditation and yoga exercises in conjunction with medical and psychological treatment.
Those participants who used meditation practices to self-regulate pain found remarkable
results: an average of 85.5% reported an improvement in pain management skills.
The meditation program, now in its seventh year, was designed and led by Pat Randolph,
Ph.D., director of Psychological Services in the Pain Center at Texas Tech Medical Center.
Focused on patients with chronic pain, pain which usually lasts six months or longer,
Randolph has designed the meditation class to teach mindfulness or "staying in the
moment" awareness.
According to Randolph, the program is based on Theravada Buddhism, an ancient Eastern
doctrine which assumes that suffering and stress is part of life, but which can be
relieved through an awareness and "letting go" of expectations.
"Sometimes pain is so overwhelming that it's like a big wave in the ocean that crests
over your head and, for a while, you just hang on for dear life until the wave
passes," Randolph explained. "When people realize that they're stuck with their
pain and it's something they have to manage, then they are more open to psychological
interventions."
In Western culture, people generally cope with pain through distraction or anasthesia.
"However, this process is only effective for a while," adds Randolph.
"Eventually your resistance to pain actually wears out."
Among the 67 patients in his study who used meditation to self-regulate pain, Randolph
found that 78 percent reported an improvement in subjective mood; 80 percent said their
ability to handle stress improved; and 86 percent recorded a higher awareness of internal
thought and feeling states. And 98 percent indicated that they had gained 'something of
lasting value' from the program.
"It's based on Eastern meditative practices, but it's devoid of religious
underpinnings," Randolph added. "In fact, in a related study, almost 90 percent
of participants indicated that the practice of meditation was 'moderately' to 'highly
consistent' with their present spiritual beliefs, most of which were of the Christian
faith."
--------------------------------------------------------------------------------------------------
10) HUMAN BRAIN TRANSPLANTATION PROTOCOL APPROVED TO REVERSE NERVE AND BRAIN
DAMAGE
Description: Scientists at Cedars-Sinai Medical Center are ready to start a human
treatment protocol that can reverse nerve and brain damage caused by stroke, Parkinson's
disease, epilepsy and spinal cord injuries. The treatment involves removal and
regeneration of carefully targeted brain cells, which are then re-introduced into the
patient, where growth continues and the brain is repaired.
LOS ANGELES -- While growing cells in petri dishes has been done for more than a century,
this old technique is being applied in ground-breaking new ways, and with space-age
equipment, at Cedars-Sinai Medical Center's Neurofunctional Surgery Center. The goal is to
produce cures for such previously incurable conditions as spinal cord injuries, stroke,
epilepsy, and Parkinson's disease.
The project was sparked by the recent discovery of human brain cells' potential for
regeneration, contradicting previous scientific assumptions. "While it is true that
brain cells don't regenerate in situ, we have found that a very small number of brain
cells, harvested and placed into a special environment, can be stimulated to regenerate,
and that regeneration continues when the cells are re-introduced into the brain,"
says Michel Levesque, M.D., Director of the Neurofunctional Surgery Center and an
internationally known neurosurgeon at Cedars-Sinai Medical Center.
Toomas Neuman, Ph.D., Director of Neurobiology at Cedars-Sinai Medical Center, and Dr.
Levesque are working together to culture a number of carefully targeted brain cells from a
patient, stimulating growth and regeneration in a carefully regulated environment, and
then re-introducing them into the patient, where the growth continues, and effects healing
and repair to previously irreparably damaged brain tissue.
"The implications of this are enormous. Right now we will use cell harvesting and
implantation to treat Parkinson's disease," says Dr. Levesque. "Treating
neurodegenerative diseases involving one type of neurotransmitter cells is comparatively
straightforward - introducing excitatory neurons or inhibitory neurons, into a particular
part of the brain. In other words, one type of cell to one location.
"Treating stroke and spinal cord injuries with regenerated cells is infinitely more
complex," says Dr. Levesque. We have to identify, grow, and re-introduce a complex
mixture of cells to restore a damaged circuitry. We're working on a human protocol for
spinal cord injury now, and hope to start treating patients with regenerated cells within
the next six months."
The process literally starts with brain surgery, says Dr. Levesque. "For epilepsy
patients who require surgery, we take a small piece of the cortex, where some of the few
brain cells capable of regeneration are located. We remove a few of those cells, store
them in our cell bank of neurons, and freeze them until we're ready to grow them in petri
dishes.
Dr. Neuman oversees the growth stimulation part of the project. "Right now we have to
remove the cells and put them into a special environment to stimulate them to begin
growing and dividing. Our goal is to eventually be able to stimulate the cells without
removing them first," says Dr. Neuman. "The cells don't spontaneously regenerate
in the body -- that's why certain types of brain injuries and illnesses are currently
incurable or irreparable.
"A variety of molecular biology tools are used to identify and stimulate the
cells," says Dr. Neuman. "We have to keep the growing cells in sterile,
biologically stable incubators -- like baby incubators -- to maintain a constant
environment. When we're ready to grow them, we put them into a special bath that includes
different growth factors. Without either one, the cells don't regenerate. If you have all
the necessary things they divide and grow. If you don't have them, these little guys
die," he adds.
"The work we're doing is based on solid scientific foundations. It began years ago,
with studies indicating that certain types of birds could produce brain cells that would
regenerate in the right circumstances. The studies moved from birds to animals. The
progression from animal brain cell regeneration to human brain cell regeneration is the
next logical step. When I began working with Dr. Levesque we discovered we had a common
interest -- our working together actually stimulated the project," says Dr. Neuman.
"When we finish developing our protocol, we'll be the first to offer this treatment
for stroke and spinal cord injuries," says Dr. Levesque. "We have a lot of
spinal cord injury patients who are interested in this type of treatment." The human
protocol is scheduled to be completed in six months, at which time cell regeneration and
re-introduction treatments can begin on humans.
-------------------------------------------------------------------------------
11) Scientists Report Brain's Central Switching System Can Be Remodeled
WINSTON-SALEM, N.C. -- The thalamus, the brain's central switching center for relaying
sensory information to the brain's somatosensory cortex, "remodels" after
sensory nerves are severed, scientists from Wake Forest University School of Medicine and
the University of California at Davis report in today's issue of Science.
"This is exciting because it could be the underpinning of the neurobiological basis
for recovery of function after stroke or damage to the nervous system," said Tim P.
Pons, Ph.D., professor of surgical sciences (neurosurgery) and professor of
physiology/pharmacology at Wake Forest.
Pons and Edward C. Jones, Ph.D., director of the Center for Neuroscience at the University
of California-Davis, said that a portion of the thalamus in nonhuman primates was
completely reorganized after the nerves relaying sensory information from the arms were
severed.
The new study follows a 1991 report from the team, also in Science, that the somatosensory
cortex itself remodels after injury.
Both reports add to mounting evidence that the brain is not fixed and unchanging after
infancy, as had been scientific dogma, but in fact can make new connections. Pons uses the
term "plasticity" to describe these changes.
"We had shown that at least one-third of the entire somatosensory cortex is capable
of reorganization and this latest work shows that at least one-third of the thalamus is
also capable of a similar type of reorganization."
The somatosensory cortex is the brain's processing center for sensory information.
The actual work involved experiments touching the face after the entire upper arm and hand
were deprived of their normal inputs. The thalamus had rewired the portions of its surface
that previously hooked into the sensory arm and hand nerves so that these portions
activated dormant nerves in the face. These nerves were stimulated with a fine glass probe
or a camel hair brush.
Pons reported there are measurable -- but tiny -- electrical discharges at that point in
the thalamus. Adjacent points on the skin activate adjacent points in the thalamus.
"When the face takes over the hand representation, the brain still interprets the
impulses as coming from the hand," he said.
The work was strikingly similar to studies of people who had undergone upper arm
amputations. When those investigators touched these amputees in certain parts of the face,
the patients had sensations that seemed to be coming from the missing limb. "This is
a very plausible explanation for phantom limb sensations and especially phantom pain
sensations," Pons said.
"We have identified the thalamus as being a critical component for that plasticity
that is exhibited at the cortex. We're not sure that these changes don't also occur at the
spinal level," Pons said, "but we doubt it is a factor because of the severe
degenerative changes seen anatomically in these animals."
While he said it was premature to speculate about direct applications of the research to
people, the researchers will be trying to harness the plasticity of the brain when it
helps -- such as after a stroke -- and halt the plasticity when it causes problems, such
as epilepsy, Parkinson's disease and Alzheimer's disease.
###
Contact: Robert Conn, Mark Wright or Jim Steele at (336) 716-4587.
12) Taking Self Regulation, Biofeedback and Self Responsibility to the Next Level.
This is a copy of a message sent to Julie Weiner, as a part of a discussion started by
Peter ROsenfeld, about how JAMAs latest issue was devoted to alternative medicince,
and how biofeedback was not represented. Someone else had stated that the reason
biofeedback was not included was that biofeedback has become part of the main stream.
Julie Weiner wrote:
>>By whom are we considered Main Line? And if we are, how come hardly anyone knows
we exist? The majority of the patients referred to me for bfb have never heard of bfb! I
doubt this happens to acupuncturists or faith healers or nutritionists! And I have yet to
meet a neurologist familiar with the research on EEG bfb and epilepsy. If we were Main
Line, wouldn't a treatment without side effects be the first line of defense instead of
the last for long-term treatment of seizure disorders? <<
So, Rob Kall replied:
The fact is, biofeedback is a CONCEPT, like medication is a concept.
There are all kinds of different biofeedback applications. Some are related, and benefit
from earlier biofeedback reseearch .
Others are different enough so the medical community rejects them because of not enough
research.
We've had great exposure over the years for stress, headache and incontinence. But I've
always believed that our biggest challenge is the fact that biofeedback takes work.
PATIENTS have been trained by the medical model, to expect treatments to be done TO them.
Biofeedback empowers them, it allows them to take responsibility, and that is not
something that many people want.
Perhaps what we need to develop, in advancing our self regulation paradigm, is a
scientific model and approach to increasing the desire to take responsibility, to want to
self regulate, to want to grasp opportunities for self empowerment.
When we can get people to see that this is a healthier way that goes beyond not being
sick, that this level of health reaches into the level of character and personal strength,
then we will be taking biofeedback's next step.
Regarding the PR issue.
The important issue is that biofeedback is a different concept than the medicine/medical
concept.
New medications get new, huge coverage, even though medications are well accepted.
We need to treat each application as a separate "media" concept. The fact is
we are "media-opportunity" rich.
But we have so few media promotion resources, because of AAPB's leadership's current
unwillingness to invest in consumer awareness. They spend $18,000 on speakers for a
meeting which has been shrinking each year, but won't spend $2000 to make the most of
fabulous publicity in Parade magazine.
So, the role of PR chair turns into a primarily passive one. What I have tried to do is
use my own journalism experience, having written myself for many national publications, to
educate reporters, not just on the current articles they are working on but on the big
picture of biofeedback. Plus, when I am contacted by reporters regarding my business, I
also promote the field in general, also giving references to the AAPB, SSNR and EEG
Spectrum websites, which I think in addition to mine, are the best ones for information
content.
I am hoping that once the PR opposing president leaves office, we can then start, with a
small annual budget ($1500-$2000 a month is minimal by all standards) to regularly send
out announcements about specific applications, so the media begin getting a regular
exposure to the depth and breadth of our field. I also would like to see more resources
put on the AAPB website, which is going through a major re-design right now.
It would be great to have some active members of the PR committee who would be willing
to put in some time on specific media research and promotion projects. It seems that AAPB
will pay for postage, so if we can get the time to make some lists, we can get some
starts. I've begun to build such lists, but do need help. Volunteers are invited
Lastly, it would be great if cooperative bridges could be built between the different
interest groups-- AAPB, SSNR, BCIA, the EEG and EMG sections and .
ROb Kall
AAPB PR chair
13) Adult Brains Make New Connections After Injury
Vanderbilt study: Adult brain cells make new connections after injury
NASHVILLE, Tenn. - The adult brain appears to have a surprisingly strong built-in capacity
for change, a study by Vanderbilt University researchers suggests, creating the
possibility for innovative treatments for brain disorders.
The seemingly limited ability of the adult brain to recover from stroke or accidental
injury has been a major stumbling block in treating brain disorders. However, the
Vanderbilt study showed new growth in cell connections following injury.
Writing in the Nov. 6 edition of Science magazine, three Vanderbilt University researchers
report that cells in the adult brain can sprout new axons, or branches, that travel
relatively long distances and make contact with new targets at distant sites in the brain.
The new growth was found in a region of the brain called the sensory cortex that receives
information from touch.
First, the normal connections among cells in the sensory cortex were studied by injecting
a harmless substance that reveals or "labels" cells and makes it possible to
trace the point-to-point nature of cell connections, according to Sherre Florence,
research assistant professor of psychology at Vanderbilt. She said that cells in the
sensory cortex normally have specific connections with neighboring cells. For example,
cells that receive information from the hand make connections only with other cells
concerned with the hand.
However, in four monkeys with hand injuries, cells had connections that spanned a much
wider area of the sensory cortex, a nearly twofold increase compared to normal monkeys.
"Cells within the injured hand cortex apparently grew connections into neighboring
cortical zones that were unimpaired by the injury," Florence said. "And cells
outside the hand region of cortex made connections to cells in the zone deprived of
sensory information because of the hand injury." (more)
According to Florence, the way the cells behaved within the zone of expanded connections
changed, suggesting that the new connections made fully effective contacts with their new
targets. This could give the new connections the opportunity to change brain function.
The new growth appeared to be triggered by the injury to the hand. None of the injuries
directly impacted the brain, but they all had the common effect of disrupting the amount
and pattern of activity being relayed to the brain from the hand.
Florence and her colleagues think that it was the massive change in activity patterns that
initiated the chain of events that led to new cell growth, not the injury itself. This
suggests that it may be possible to coax more flexibility out of the adult brain, taking
advantage of these natural processes, in contrast to other lines of research where
chemicals were administered to facilitate cell growth.
The ultimate goal is to be able to reproduce the conditions necessary for axon growth, to
help cells in the adult brain form effective new long-distance connections. This might
make it possible to reverse some of the effects of damage to the nervous system from
spinal cord injury or brain disorders such as stroke.
Other researchers who worked on the project were Jon H. Kaas, Centennial Professor
Psychology and Professor of Cell Biology at Vanderbilt; and H.B. Taub, a Vanderbilt
graduate student in psychology.
For more news about Vanderbilt, visit the Vanderbilt web site at www.vanderbilt.edu/
Ann Marie Deer Owens, (615) 322-NEWS
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